Examples · Reconstitution
Worked example
Reconstitution - practice problem 12
The prescriber orders 250 mg of methylprednisolone IV. The vial directs: add 1 mL of diluent to yield 40 mg/mL.
Ordered dose250 mg
After reconstitution40 mg/mL
Diluent1 mL
How many milliliters should the nurse draw up?
Answer: 6.25 mL
Step-by-step solution
1. Read the concentration after reconstitution
Add 1 mL diluent → 40 mg per 1 mL
2. Set up dimensional analysis so mg cancels
250 mg × ( 1 mL ÷ 40 mg )
3. Cancel mg and solve
= 250 ÷ 40 mL
= 6.25 mL
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