Examples · Reconstitution
Worked example
Reconstitution - practice problem 8
The prescriber orders 40 mg of methylprednisolone IV. A 125 mg vial directs: add 2 mL of diluent to yield 62.5 mg/mL.
Ordered dose40 mg
Vial125 mg
Diluent2 mL
After reconstitution62.5 mg/mL
How many milliliters should the nurse draw up?
Answer: 0.64 mL
Step-by-step solution
1. Read the concentration after reconstitution
Add 2 mL diluent → 62.5 mg per 1 mL
2. Set up dimensional analysis so mg cancels
40 mg × ( 1 mL ÷ 62.5 mg )
3. Cancel mg and solve
= 40 ÷ 62.5 mL
= 0.64 mL
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