Examples · Reconstitution
Worked example
Reconstitution - practice problem 7
The prescriber orders 400 mg of acyclovir IV. A 500 mg vial directs: add 10 mL of diluent to yield 50 mg/mL.
Ordered dose400 mg
Vial500 mg
Diluent10 mL
After reconstitution50 mg/mL
How many milliliters should the nurse draw up?
Answer: 8 mL
Step-by-step solution
1. Read the concentration after reconstitution
Add 10 mL diluent → 50 mg per 1 mL
2. Set up dimensional analysis so mg cancels
400 mg × ( 1 mL ÷ 50 mg )
3. Cancel mg and solve
= 400 ÷ 50 mL
= 8 mL
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