Worked example

Reconstitution - practice problem 6

The prescriber orders 125 mg of methylprednisolone IV. The vial directs: add 1 mL of diluent to yield 40 mg/mL.

Ordered dose125 mg
After reconstitution40 mg/mL
Diluent1 mL

How many milliliters should the nurse draw up?

Answer: 3.13 mL

Step-by-step solution

1. Read the concentration after reconstitution
Add 1 mL diluent → 40 mg per 1 mL
2. Set up dimensional analysis so mg cancels
125 mg × ( 1 mL ÷ 40 mg )
3. Cancel mg and solve
= 125 ÷ 40 mL
= 3.13 mL

More reconstitution examples